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Knowledge is power

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2012; 48:218–25. 5 Braun-Falco M, Friedrichson E, Ring J. Subepidermal cleft formation as a diagnostic marker for cutaneous malignant melanoma. Hum Pathol 2005; 36:412–15. 6 Bønnelykke-Behrndtz LM, Schmidt H, Damsgaard… Click to show full abstract

2012; 48:218–25. 5 Braun-Falco M, Friedrichson E, Ring J. Subepidermal cleft formation as a diagnostic marker for cutaneous malignant melanoma. Hum Pathol 2005; 36:412–15. 6 Bønnelykke-Behrndtz LM, Schmidt H, Damsgaard TE et al. Consumption of the epidermis: a suggested precursor of ulceration associated with increased proliferation of melanoma cells. Am J Dermatopathol 2015; 37:841–5. 7 Ellis R, Tang D, Nasr B et al. Epidermal autophagy and beclin 1 regulator 1 and loricrin: a paradigm shift in the prognostication and stratification of the American Joint Committee on Cancer stage I melanomas. Br J Dermatol 2020; 182:156–65. 8 Cosgarea I, McConnell AT, Ewen T et al. Melanoma secretion of transforming growth factor-b2 leads to loss of epidermal AMBRA1 threatening epidermal integrity and facilitating tumour ulceration. Br J Dermatol 2022; 186:694–704. 9 Javelaud D, Alexaki VI, Mauviel A. Transforming growth factor-b in cutaneous melanoma. Pigment Cell Melanoma Res 2008; 21:123–32. 10 Dalton SJ, Whiting CV, Bailey JR et al. Mechanisms of chronic skin ulceration linking lactate, transforming growth factor-b, vascular endothelial growth factor, collagen remodeling, collagen stability, and defective angiogenesis. J Invest Dermatol 2007; 127:958–68.

Keywords: knowledge power; transforming growth; growth factor; melanoma

Journal Title: British Journal of Dermatology
Year Published: 2022

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