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Targeting the itch–scratch vicious circle in atopic eczema

et al . 4 report two long-term studies assessing the efficacy and tolerance of nemolizumab (a humanized IL-31RA monoclonal antibody) in addition to topical anti-inflammatory agents in adolescent and adult… Click to show full abstract

et al . 4 report two long-term studies assessing the efficacy and tolerance of nemolizumab (a humanized IL-31RA monoclonal antibody) in addition to topical anti-inflammatory agents in adolescent and adult patients with AE. The paper merges the results of the 52-week open extension phase of a previously published 16-week phase III randomized controlled trial (RCT) of nemolizumab vs. placebo (143 and 72 participants, respectively) 5 and an open-label study including 88 participants.

Keywords: scratch vicious; vicious circle; atopic eczema; targeting itch; itch scratch; circle atopic

Journal Title: British Journal of Dermatology
Year Published: 2022

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