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Distinct skin microbiome community structures in congenital ichthyosis

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The ichthyoses are rare genetic keratinizing disorders that share the characteristics of an impaired epidermal barrier and increased risk of microbial infections. Although ichthyotic diseases share a T helper (Th)… Click to show full abstract

The ichthyoses are rare genetic keratinizing disorders that share the characteristics of an impaired epidermal barrier and increased risk of microbial infections. Although ichthyotic diseases share a T helper (Th) 17 cell immune signature, including increased expression of antimicrobial peptides, the skin microbiota of ichthyoses is virtually unexplored.

Keywords: distinct skin; skin microbiome; congenital ichthyosis; structures congenital; microbiome community; community structures

Journal Title: British Journal of Dermatology
Year Published: 2022

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