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Mutation profiling by targeted sequencing of “triple‐negative” essential thrombocythaemia patients

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Burger, J.A., Tedeschi, A., Barr, P.M., Robak, T., Owen, C., Ghia, P., Bairey, O., Hillmen, P., Bartlett, N.L., Li, J., Simpson, D., Grosicki, S., Devereux, S., McCarthy, H., Coutre, S.,… Click to show full abstract

Burger, J.A., Tedeschi, A., Barr, P.M., Robak, T., Owen, C., Ghia, P., Bairey, O., Hillmen, P., Bartlett, N.L., Li, J., Simpson, D., Grosicki, S., Devereux, S., McCarthy, H., Coutre, S., Quach, H., Gaidano, G., Maslyak, Z., Stevens, D.A., Janssens, A., Offner, F., Mayer, J., O’Dwyer, M., Hellmann, A., Schuh, A., Siddiqi, T., Polliack, A., Tam, C.S., Suri, D., Cheng, M., Clow, F., Styles, L., James, D.F. & Kipps, T.J. (2015) Ibrutinib as initial therapy for patients with chronic lymphocytic leukemia. New England Journal of Medicine, 373, 2425–2437. Byrd, J.C., Brown, J.R., O’Brien, S., Barrientos, J.C., Kay, N.E., Reddy, N.M., Coutre, S., Tam, C.S., Mulligan, S.P., Jaeger, U., Devereux, S., Barr, P.M., Furman, R.R., Kipps, T.J., Cymbalista, F., Pocock, C., Thornton, P., Caligaris-Cappio, F., Robak, T., Delgado, J., Schuster, S.J., Montillo, M., Schuh, A., de Vos, S., Gill, D., Bloor, A., Dearden, C., Moreno, C., Jones, J.J., Chu, A.D., Fardis, M., McGreivy, J., Clow, F., James, D.F. & Hillmen, P. (2014) Ibrutinib versus ofatumumab in previously treated chronic lymphoid leukemia. New England Journal of Medicine, 371, 213–223. Scheers, E., Leclercq, L., de Jong, J., Bode, N., Bockx, M., Laenen, A., Cuyckens, F., Skee, D., Murphy, J., Sukbuntherng, J. & Mannens, G. (2015) Absorption, metabolism, and excretion of oral (1)(4)C radiolabeled ibrutinib: an openlabel, phase I, single-dose study in healthy men. Drug Metabolism and Disposition, 43, 289–297. Shanafelt, T.D., Rabe, K.G., Hanson, C.A., Call, T.G., Schwager, S., Parikh, S.A., Nasr, S.H. & Leung, N. (2013) Renal disease in patients with Chronic Lymphocytic Leukemia (CLL). Blood, 122, 5302–5302.

Keywords: medicine; profiling targeted; mutation profiling; sequencing triple; targeted sequencing; triple negative

Journal Title: British Journal of Haematology
Year Published: 2018

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