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NICE NG89 recommendations for extended pharmacological thromboprophylaxis – is it justified and is it cost effective: a rebuttal from the British Society for Haematology – response to Lester et al

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S., Saliba, J., Mouton, C., Leroy, E., Harutyunyan, A.S., Abgrall, J.-F., Favier, R., Toussaint, A., Solary, E., Kralovics, R., Constantinescu, S.N., Najman, A., Vainchenker, W., Plo, I. & Bellann eChantelot,… Click to show full abstract

S., Saliba, J., Mouton, C., Leroy, E., Harutyunyan, A.S., Abgrall, J.-F., Favier, R., Toussaint, A., Solary, E., Kralovics, R., Constantinescu, S.N., Najman, A., Vainchenker, W., Plo, I. & Bellann eChantelot, C. (2014) Germ-line JAK2 mutations in the kinase domain are responsible for hereditary thrombocytosis and are resistant to JAK2 and HSP90 inhibitors. Blood, 123, 1372– 1383. Mead, A.J., Rugless, M.J., Jacobsen, S.E.W. & Schuh, A. (2012) Germline JAK2 mutation in a family with hereditary thrombocytosis. The New England Journal of Medicine, 366, 967–969. Mead, A.J., Chowdhury, O., Pecquet, C., Dusa, A., Woll, P., Atkinson, D., Burns, A., Score, J., Rugless, M., Clifford, R., Moule, S., Bienz, N., Vyas, P., Cross, N., Gale, R.E., Henderson, S., Constantinescu, S.N., Schuh, A. & Jacobsen, S.E. (2013) Impact of isolated germline JAK2V617I mutation on human hematopoiesis. Blood, 121, 4156–4165.

Keywords: extended pharmacological; haematology; nice ng89; pharmacological thromboprophylaxis; recommendations extended; ng89 recommendations

Journal Title: British Journal of Haematology
Year Published: 2019

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