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Outcomes and management of patients with mantle cell lymphoma after progression on brexucabtagene autoleucel therapy

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yet to recover to the pre-COVID-19 levels. Maintaining capacity to treat patients with high-risk haematological malignancies is essential requiring adherence to guidelines designed to reduce the spread of infection and… Click to show full abstract

yet to recover to the pre-COVID-19 levels. Maintaining capacity to treat patients with high-risk haematological malignancies is essential requiring adherence to guidelines designed to reduce the spread of infection and create a safe environment for treating a vulnerable patient population. The utility of staff screening is uncertain and is currently being studied prospectively as part of the SIREN study which aims to assess the incidence of COVID-19 in healthcare workers and to determine the extent to which anti-SARSCov-2 antibodies provide protective immunity. However, until such time as the results of this and other trials are available, screening asymptomatic healthcare workers in transplant units represents a potentially effective means to reduce the risk of viral transmission between patients and staff. The results of this survey highlight significant inconsistency in testing strategies employed between UK transplant centres and a number of barriers to implementation were identified including capacity and local policies which could be overcome with adherence to national and international guidance and prioritisation of test availability in this patient group.

Keywords: cell lymphoma; outcomes management; patients mantle; mantle cell; lymphoma progression; management patients

Journal Title: British Journal of Haematology
Year Published: 2020

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