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Biclonal evolution of chronic lymphocytic leukaemia

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et al. Identifying genetic variants and pathways associated with extreme levels of fetal hemoglobin in sickle cell disease in Tanzania. BMC Med Genet. 2020;21:125. 12. Xu J, Bauer DE, Kerenyi… Click to show full abstract

et al. Identifying genetic variants and pathways associated with extreme levels of fetal hemoglobin in sickle cell disease in Tanzania. BMC Med Genet. 2020;21:125. 12. Xu J, Bauer DE, Kerenyi MA, Vo TD, Hou S, Hsu Y-J, et al. Corepressordependent silencing of fetal hemoglobin expression by BCL11A. Proc Natl Acad Sci USA. 2013;110:6518–23. 13. Weber L, Frati G, Felix T, Hardouin G, Casini A, Wollenschlaeger C, et al. Editing a c-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype. Sci Adv. 2020;6:eaay9392. 14. Steinberg MH. Fetal hemoglobin in sickle cell anemia. Blood. 2020;118:19– 27. 15. Bauer DE, Kamran SC, Lessard S, Xu J, Fujiwara Y, Lin C, et al. An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level. Science. 2013;342:253–7.

Keywords: fetal hemoglobin; biclonal evolution; lymphocytic leukaemia; evolution chronic; chronic lymphocytic; sickle cell

Journal Title: British Journal of Haematology
Year Published: 2021

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