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New biomarker paves the way for a clinical trial for neurodegeneration in Langerhans cell histiocytosis

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Neurodegeneration in Langerhans cell histiocytosis (ND‐LCH) is a major clinical issue requiring urgent resolution. Sveijer et al. showed that plasma neurofilament light protein is a promising biomarker for screening patients… Click to show full abstract

Neurodegeneration in Langerhans cell histiocytosis (ND‐LCH) is a major clinical issue requiring urgent resolution. Sveijer et al. showed that plasma neurofilament light protein is a promising biomarker for screening patients with ND‐LCH and determining the therapeutic effect of a mitogen‐activated protein kinase inhibitor. Therefore, this can be a powerful tool for conducting clinical trials for ND‐LCH.

Keywords: neurodegeneration langerhans; cell histiocytosis; langerhans cell; new biomarker

Journal Title: British Journal of Haematology
Year Published: 2022

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