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Transplant‐associated thrombotic microangiopathy remains a lethal complication of haematopoietic stem cell transplant and not all patients respond to terminal complement inhibitors. Qi et al. show that hypoxia‐inducible factor‐1α (HIF‐1α) may… Click to show full abstract
Transplant‐associated thrombotic microangiopathy remains a lethal complication of haematopoietic stem cell transplant and not all patients respond to terminal complement inhibitors. Qi et al. show that hypoxia‐inducible factor‐1α (HIF‐1α) may be a previously unrecognized driver of this endothelial injury syndrome.
Keywords:
thrombotic microangiopathy;
transplant;
associated thrombotic;
complements complement;
transplant associated
Journal Title: British Journal of Haematology
Year Published: 2022
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Journal Title: British Journal of Haematology
Year Published: 2022
Link to full text (if available)
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recommendations!