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The role of prostaglandin and E series prostaglandin receptor type 4 receptors in the development of bladder overactivity in a rat model of chemically induced prostatic inflammation

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To evaluate, using a rat model of non‐bacterial prostatic inflammation, the prostaglandin production and expression profiles of E‐series prostaglandin (EP) receptor subtypes, which are reportedly implicated in the development of… Click to show full abstract

To evaluate, using a rat model of non‐bacterial prostatic inflammation, the prostaglandin production and expression profiles of E‐series prostaglandin (EP) receptor subtypes, which are reportedly implicated in the development of overactive bladder, in the bladder mucosa, and to investigate the effect of EP receptor type 4 (EP4) blockade on bladder overactivity after prostatic inflammation.

Keywords: prostatic inflammation; prostaglandin; bladder; receptor; rat model

Journal Title: BJU International
Year Published: 2019

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