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The majority of the severe vascular complications in fibrosis are a consequence of a deregulated activity of mediators controlling vasomotor tone. One of the most important of these mediators is… Click to show full abstract
The majority of the severe vascular complications in fibrosis are a consequence of a deregulated activity of mediators controlling vasomotor tone. One of the most important of these mediators is endothelin‐1 (ET‐1). Here, we have investigated the role of proteinase‐activated receptor 2 (PAR2) in the vascular dysfunction in a model of fibrosis, using tight‐skin (Tsk) mice.
Keywords:
activated receptor;
tight skin;
proteinase activated
Journal Title: British Journal of Pharmacology
Year Published: 2017
Link to full text (if available)
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Journal Title: British Journal of Pharmacology
Year Published: 2017
Link to full text (if available)
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recommendations!