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Canonical hedgehog signalling regulates hepatic stellate cell‐mediated angiogenesis in liver fibrosis

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Hepatic stellate cells (HSCs) are liver‐specific pericytes regulating angiogenesis during liver fibrosis. We aimed to elucidate the mechanisms by which hedgehog signalling regulated HSC angiogenic properties and to validate the… Click to show full abstract

Hepatic stellate cells (HSCs) are liver‐specific pericytes regulating angiogenesis during liver fibrosis. We aimed to elucidate the mechanisms by which hedgehog signalling regulated HSC angiogenic properties and to validate the therapeutic implications.

Keywords: hedgehog signalling; angiogenesis liver; hepatic stellate; liver fibrosis

Journal Title: British Journal of Pharmacology
Year Published: 2017

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