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Protein tyrosine phosphatase 1B (PTP1B) negatively regulates insulin signalling by tyrosine dephosphorylation of the insulin receptor. It is a highly validated target for type 2 diabetes therapeutics. Here, the anti‐diabetic… Click to show full abstract
Protein tyrosine phosphatase 1B (PTP1B) negatively regulates insulin signalling by tyrosine dephosphorylation of the insulin receptor. It is a highly validated target for type 2 diabetes therapeutics. Here, the anti‐diabetic effects of HPN were evaluated in the diabetic BKS db mice.
Keywords:
cell permeability;
selectivity cell;
tyrosine phosphatase;
protein tyrosine
Journal Title: British Journal of Pharmacology
Year Published: 2018
Link to full text (if available)
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Journal Title: British Journal of Pharmacology
Year Published: 2018
Link to full text (if available)
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recommendations!