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Systemically delivered statins can blunt airway inflammation in ovalbumin‐challenged mice. However, in asthma clinical trials the beneficial effects of introducing oral statins are not compelling. We have invetigated this discrepancy… Click to show full abstract
Systemically delivered statins can blunt airway inflammation in ovalbumin‐challenged mice. However, in asthma clinical trials the beneficial effects of introducing oral statins are not compelling. We have invetigated this discrepancy using a clinically relevant murine model of allergic asthma, and by including a prophylactic study arm.
Keywords:
prophylactic benefits;
model allergic;
murine model;
systemically delivered;
allergic asthma
Journal Title: British Journal of Pharmacology
Year Published: 2018
Link to full text (if available)
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Journal Title: British Journal of Pharmacology
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!