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The mineralocorticoid receptor (MR) contributes to fibrosis in various tissues, and MR antagonists, like eplerenone, are used to prevent fibrosis. The role of MR antagonists in hepatic fibrosis and cirrhosis… Click to show full abstract
The mineralocorticoid receptor (MR) contributes to fibrosis in various tissues, and MR antagonists, like eplerenone, are used to prevent fibrosis. The role of MR antagonists in hepatic fibrosis and cirrhosis is unknown. Here, we investigated the role of MRs and eplerenone in cirrhosis development.
Keywords:
receptor antagonist;
cirrhosis;
mineralocorticoid receptor;
eplerenone;
selective mineralocorticoid
Journal Title: British Journal of Pharmacology
Year Published: 2018
Link to full text (if available)
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Journal Title: British Journal of Pharmacology
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!