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Immunomodulatory tetracyclines are well‐characterized drugs with a pharmacological potential beyond their antibiotic properties. Specifically, minocycline and doxycycline have shown beneficial effects in experimental colitis, although pro‐inflammatory actions have also been… Click to show full abstract
Immunomodulatory tetracyclines are well‐characterized drugs with a pharmacological potential beyond their antibiotic properties. Specifically, minocycline and doxycycline have shown beneficial effects in experimental colitis, although pro‐inflammatory actions have also been described in macrophages. Therefore, we aimed to characterize the mechanism behind their effect in acute intestinal inflammation.
Keywords:
intestinal inflammatory;
inflammatory response;
immunomodulatory tetracyclines;
tetracyclines shape;
response inducing;
shape intestinal
Journal Title: British Journal of Pharmacology
Year Published: 2018
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Journal Title: British Journal of Pharmacology
Year Published: 2018
Link to full text (if available)
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recommendations!