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The midbrain periaqueductal grey (PAG) plays a central role in modulating pain through a descending pathway that projects indirectly to the spinal cord via the rostroventral medial medulla (RVM). While… Click to show full abstract
The midbrain periaqueductal grey (PAG) plays a central role in modulating pain through a descending pathway that projects indirectly to the spinal cord via the rostroventral medial medulla (RVM). While opioids are potent analgesics that target the PAG, their cellular actions on descending projection neurons are unclear.
Keywords:
midbrain periaqueductal;
presynaptic disinhibition;
periaqueductal grey;
opioid presynaptic
Journal Title: British Journal of Pharmacology
Year Published: 2020
Link to full text (if available)
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Journal Title: British Journal of Pharmacology
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!