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Bleomycin: A novel osteogenesis inhibitor of dental follicle cells via a TGF‐β1/SMAD7/RUNX2 pathway

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Tooth eruption is a complicated process regulated by the dental follicles (DF). Our recent study discovered that tooth eruption was inhibited upon injection of bleomycin into DF. However, the mechanisms… Click to show full abstract

Tooth eruption is a complicated process regulated by the dental follicles (DF). Our recent study discovered that tooth eruption was inhibited upon injection of bleomycin into DF. However, the mechanisms were unknown.

Keywords: dental follicle; bleomycin novel; follicle cells; inhibitor dental; novel osteogenesis; osteogenesis inhibitor

Journal Title: British Journal of Pharmacology
Year Published: 2020

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