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Chronic fluoxetine treatment impairs motivation and reward learning by affecting neuronal plasticity in the central amygdala

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The therapeutic effects of fluoxetine are believed to be due to increasing neuronal plasticity and reversing some learning deficits. Nevertheless, a growing amount of evidence shows adverse effects of this… Click to show full abstract

The therapeutic effects of fluoxetine are believed to be due to increasing neuronal plasticity and reversing some learning deficits. Nevertheless, a growing amount of evidence shows adverse effects of this drug on cognition and some forms of neuronal plasticity.

Keywords: plasticity; chronic fluoxetine; neuronal plasticity; impairs motivation; treatment impairs; fluoxetine treatment

Journal Title: British Journal of Pharmacology
Year Published: 2020

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