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Excessive oxidative stress can induce PARP1‐mediated programmed necrotic cell death, termed parthanatos. Inhibition of parthanatos may be therapeutically beneficial in a wide array of diseases associated with tissue injury and… Click to show full abstract
Excessive oxidative stress can induce PARP1‐mediated programmed necrotic cell death, termed parthanatos. Inhibition of parthanatos may be therapeutically beneficial in a wide array of diseases associated with tissue injury and inflammation. Our goal was to identify novel molecules inhibiting parthanatos.
Keywords:
content screening;
screening identifies;
stress;
high content;
identifies inhibitors;
oxidative stress
Journal Title: British Journal of Pharmacology
Year Published: 2020
Link to full text (if available)
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Journal Title: British Journal of Pharmacology
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!