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Cannabidiol (CBD) is a non‐euphorigenic component of Cannabis sativa that prevents the development of paclitaxel‐induced mechanical sensitivity in a mouse model of chemotherapy‐induced peripheral neuropathy (CIPN). We recently reported that… Click to show full abstract
Cannabidiol (CBD) is a non‐euphorigenic component of Cannabis sativa that prevents the development of paclitaxel‐induced mechanical sensitivity in a mouse model of chemotherapy‐induced peripheral neuropathy (CIPN). We recently reported that the CBD structural analogue KLS‐13019 shows efficacy in an in vitro model of CIPN. The present study was to characterize the behavioural effects of KLS‐13019 compared to CBD and morphine in mouse models of CIPN, nociceptive pain and reinforcement.
Journal Title: British Journal of Pharmacology
Year Published: 2021
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