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HERG blocking drugs known for their propensity to trigger Torsades de Pointes (TdP) were reported to induce a sympatho‐vagal coactivation and to enhance High Frequency heart rate (HFHR) and QT… Click to show full abstract
HERG blocking drugs known for their propensity to trigger Torsades de Pointes (TdP) were reported to induce a sympatho‐vagal coactivation and to enhance High Frequency heart rate (HFHR) and QT oscillations (HFQT) in telemetric data. The present work aimed to characterize the underlying mechanism(s) leading to these autonomic changes.
Keywords:
blocking drugs;
haemodynamic side;
herg blocking;
side effects;
contribution haemodynamic
Journal Title: British Journal of Pharmacology
Year Published: 2022
Link to full text (if available)
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Journal Title: British Journal of Pharmacology
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!