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Over past decades, targeted therapies and immunotherapy have improved survival and reduced the morbidity of patients with BRAF‐mutated melanoma. However, drug resistance and relapse hinder overall success. Therefore, there is… Click to show full abstract
Over past decades, targeted therapies and immunotherapy have improved survival and reduced the morbidity of patients with BRAF‐mutated melanoma. However, drug resistance and relapse hinder overall success. Therefore, there is an urgent need for novel compounds with therapeutic efficacy against BRAF‐melanoma. This prompted us to investigate the antiproliferative profile of a tachykinin‐peptide from the Octopus kaurna, Octpep‐1 in melanoma.
Keywords:
tachykinin;
tachykinin domain;
melanoma;
peptide;
conformation tachykinin;
structural conformation
Journal Title: British Journal of Pharmacology
Year Published: 2022
Link to full text (if available)
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Journal Title: British Journal of Pharmacology
Year Published: 2022
Link to full text (if available)
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recommendations!