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A plant‐derived glucocorticoid receptor modulator with potency to attenuate the side effects of glucocorticoid therapy

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Continuous efforts have been made to move towards maintaining the beneficial anti‐inflammatory functions of glucocorticoids (GCs) while minimizing side effects. Here, we investigated the selective glucocorticoid receptor (GR) modulator‐like properties… Click to show full abstract

Continuous efforts have been made to move towards maintaining the beneficial anti‐inflammatory functions of glucocorticoids (GCs) while minimizing side effects. Here, we investigated the selective glucocorticoid receptor (GR) modulator‐like properties of a plant‐derived compound caesaldekarin e (CA‐e).

Keywords: side effects; receptor modulator; glucocorticoid receptor; plant derived

Journal Title: British Journal of Pharmacology
Year Published: 2022

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