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Cannabinoids are a promising therapeutic avenue for chronic pain. However, clinical trials often fail to report analgesic efficacy of cannabinoids. Inhibition of voltage gate calcium (Cav) channels is one mechanism… Click to show full abstract
Cannabinoids are a promising therapeutic avenue for chronic pain. However, clinical trials often fail to report analgesic efficacy of cannabinoids. Inhibition of voltage gate calcium (Cav) channels is one mechanism through which cannabinoids may produce analgesia. We hypothesized that cannabinoids and cannabinoid receptor agonists target different types of Cav channels through distinct mechanisms.
Keywords:
calcium;
cav3 cav2;
cav2 calcium;
calcium channels;
differential regulation;
regulation cav3
Journal Title: British Journal of Pharmacology
Year Published: 2023
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Journal Title: British Journal of Pharmacology
Year Published: 2023
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!