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Repeated amino acid sequences in proteins are widely found, and the glycine–serine–alanine repeat is an element with a general propensity to form β‐sheet aggregates as found in key pathological factors,… Click to show full abstract
Repeated amino acid sequences in proteins are widely found, and the glycine–serine–alanine repeat is an element with a general propensity to form β‐sheet aggregates as found in key pathological factors, in several neurodegenerative diseases. Such properties of this repeat may guide development of disease‐modifying therapies for neurodegenerative disease. However, details of its role and underlying mechanism(s) remain largely unknown.
Keywords:
rich peptide;
glycine serine;
serine alanine;
alanine rich
Journal Title: British journal of pharmacology
Year Published: 2023
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Journal Title: British journal of pharmacology
Year Published: 2023
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!