Hyoscine butylbromide (HBB) has a low oral (PO) bioavailability. Further, limited data on its activity on non‐gastrointestinal (GI) smooth muscle spasms after oral dosing are available, causing its effects beyond… Click to show full abstract
Hyoscine butylbromide (HBB) has a low oral (PO) bioavailability. Further, limited data on its activity on non‐gastrointestinal (GI) smooth muscle spasms after oral dosing are available, causing its effects beyond the GI tract to be questioned. This pharmacokinetic/pharmacodynamic (PK/PD) study, conducted using female rats, aimed to cover this gap.
Keywords:
exerts spasmolytic;
hyoscine;
oral hyoscine;
butylbromide exerts;
spasmolytic effects;
hyoscine butylbromide
Journal Title: British Journal of Pharmacology
Year Published: 2025
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Journal Title: British Journal of Pharmacology
Year Published: 2025
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!