Dupilumab is a human monoclonal IgG4 antibody that inhibits IL-4 and IL-13 signalling by binding specifically to the IL-4Rα subunit, shared by both the IL4 and IL-13 receptor complexes (1)… Click to show full abstract
Dupilumab is a human monoclonal IgG4 antibody that inhibits IL-4 and IL-13 signalling by binding specifically to the IL-4Rα subunit, shared by both the IL4 and IL-13 receptor complexes (1) recently introduced for the treatment of severe atopic dermatitis (AD). We report a case of severe AD associated with cold urticaria that healed shortly after starting Dupilumab therapy. This article is protected by copyright. All rights reserved.
               
Click one of the above tabs to view related content.