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Successful use of guselkumab in the treatment of severe hidradenitis suppurativa

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Hidradenitis Suppurativa (HS) is a chronic incurable disease of apocrine gland-bearing skin characterised by double comedones, recurrent nodules, draining tracts and scarring predominantly in the axilla, groin and inframammary folds.… Click to show full abstract

Hidradenitis Suppurativa (HS) is a chronic incurable disease of apocrine gland-bearing skin characterised by double comedones, recurrent nodules, draining tracts and scarring predominantly in the axilla, groin and inframammary folds. Adalimumab and Infliximab are recommended for use in HS Hurley stage 2-3 and there are several reported cases and one case series of successful treatment with Ustekinumab which blocks the p40 subunit of IL-12 and IL-231 . We report a case of successful treatment of HS with a monoclonal antibody (Guselkumab) to the p19 subunit of IL-23.

Keywords: treatment; guselkumab; hidradenitis suppurativa; use

Journal Title: Clinical and Experimental Dermatology
Year Published: 2020

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