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Hidradenitis suppurativa and amyloidosis: a possible association with the pyrin inflammasome

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We read the article by Kridin et al1 with great interest. In this cross-sectional study, seven(0.2%) cases of amyloidosis were reported from a predominantly Jewish sample of 4417 patients with… Click to show full abstract

We read the article by Kridin et al1 with great interest. In this cross-sectional study, seven(0.2%) cases of amyloidosis were reported from a predominantly Jewish sample of 4417 patients with hidradenitis suppurativa(HS). Secondary AA-type amyloidosis may be encountered throughout the long-standing course of various inflammatory diseases including HS. But the association of amyloidosis and HS is intriguing considering HS's own autoinflammatory nature.

Keywords: hidradenitis suppurativa; suppurativa amyloidosis; amyloidosis; amyloidosis possible; possible association

Journal Title: Clinical and Experimental Dermatology
Year Published: 2021

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