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The Koebner phenomenon seen in a case of drug-induced granular C3 dermatosis.

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Granular C3 dermatosis (GCD), first described by Hashimoto et al. in 2016, is characterised by granular deposition of C3 and C5b-9, but not immunoglobulin (Ig)A, IgG or IgM, at the… Click to show full abstract

Granular C3 dermatosis (GCD), first described by Hashimoto et al. in 2016, is characterised by granular deposition of C3 and C5b-9, but not immunoglobulin (Ig)A, IgG or IgM, at the epidermal basement membrane zone (BMZ) by direct immunofluorescence (DIF).1,2 GCD clinically manifests as vesicles or tense blisters with erythema. Histopathologically, GCD presents mainly subepidermal blisters, at times with oedematous and spongiotic changes, without apparent intraepidermal blister, in the epidermis.1,2.

Keywords: seen case; koebner phenomenon; case drug; granular dermatosis; phenomenon seen; dermatosis

Journal Title: Clinical and experimental dermatology
Year Published: 2021

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