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Secukinumab treatment and vaccination efficacy.

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Dear Editor, Secukinumab, a monoclonal antibody against interleukin (IL)-17A, is used to treat psoriasis and psoriatic arthritis. The effect of this treatment on COVID-19 vaccination is not well characterized. While… Click to show full abstract

Dear Editor, Secukinumab, a monoclonal antibody against interleukin (IL)-17A, is used to treat psoriasis and psoriatic arthritis. The effect of this treatment on COVID-19 vaccination is not well characterized. While IL-17 deficiency states are associated with mucocutaneous infection with Candida albicans, there is no apparent increased risk of viral infection, and redundancy between IL-17A and IL-17F limits the impact of IL-17A deficiency on immune responsiveness.

Keywords: dermatology; vaccination efficacy; treatment; secukinumab treatment; treatment vaccination; vaccination

Journal Title: Clinical and experimental dermatology
Year Published: 2021

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