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Atypical Wiskott–Aldrich syndrome without thrombocytopenia partially responding to omalizumab therapy

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Primary immunodeficiencies with eczema can be easily misdiagnosed as atopic eczema, and thus require a high degree of awareness for diagnosis. Wiskott-Aldrich syndrome (WAS) is a rare disease and the… Click to show full abstract

Primary immunodeficiencies with eczema can be easily misdiagnosed as atopic eczema, and thus require a high degree of awareness for diagnosis. Wiskott-Aldrich syndrome (WAS) is a rare disease and the fact that WAS without microthrombocytopenia has not been reported to date makes this case more interesting. As the patient's predominant problem was eczema and he had high circulating IgE antibodies in his serum, omalizumab was chosen as an appropriate steroid-sparing treatment option, as it has been shown to be effective in previous studies.

Keywords: aldrich syndrome; wiskott aldrich; atypical wiskott; syndrome without

Journal Title: Clinical and Experimental Dermatology
Year Published: 2022

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