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can warm the perifollicular skin, thus helping preserve melanogenesis and maintain pigmentation. Pigmentary retention over the blood vessels was first illustrated in 1984 and verified in other literature. The skin… Click to show full abstract
can warm the perifollicular skin, thus helping preserve melanogenesis and maintain pigmentation. Pigmentary retention over the blood vessels was first illustrated in 1984 and verified in other literature. The skin overlying the blood vessels is warmer than the surrounding depigmented skin, which may explain this phenomenon. The salt-and-pepper appearance is strongly associated with dcSSc, increased risk of pruritus and joint contractures. It could be a valuable tool to detect dcSSc at an early stage, thus leading to early interventions. Supravenous pigment retention is rarely described in SSc, and we therefore present a representative image of this interesting clinical finding. The pathogenesis of the sparing phenomenon in ‘salt-and-pepper’ appearance remains to be elucidated.
Journal Title: Clinical and Experimental Dermatology
Year Published: 2022
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