LAUSR

Cryosurgery using liquid nitrogen a preserve of UK dermatology cryosurgery at nozzle the cryosurgery device to the skin approximately 10 mm the skin surface liquid nitrogen is discharged, which immediately boils and vaporizes in the air The liquid nitrogen aerosol lowers the skin temperature rapidly and a freeze-ball (ice-ball) is produced. This freeze-ball differentially damages tissue structures and cells; malignant cells require cooling to at least (cid:1) 50 ° C for destruction, whereas melanocytes are more temperature-sensitive (dying at temperatures < (cid:1) 50 ° C) and their destruction is the likely cause of potential dyspigmentation post cryosurgery. Isolated superficial basal cell carcinomas (sBCCs) in noncritical sites such as the main body area are reason-able candidates for cryosurgery and supported by the British Association of Dermatologists guideline on the management of BCCs.