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The effect of high‐dose vitamin D supplementation on muscular function and quality of life in postmenopausal women—A randomized controlled trial

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Observational studies have suggested positive associations between serum 25‐hydroxyvitamin D (25(OH)D) levels and muscular strength, balance and quality of life. Our aim was to examine whether high‐dose vitamin D supplementation… Click to show full abstract

Observational studies have suggested positive associations between serum 25‐hydroxyvitamin D (25(OH)D) levels and muscular strength, balance and quality of life. Our aim was to examine whether high‐dose vitamin D supplementation would improve these measures as compared to standard‐dose vitamin D, as well as the possible muscular effects of single nucleotide polymorphisms (SNPs) in genes encoding vitamin D‐related enzymes.

Keywords: high dose; quality life; vitamin supplementation; dose vitamin

Journal Title: Clinical Endocrinology
Year Published: 2017

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