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Identification of somatic TERT promoter mutations in familial nonmedullary thyroid carcinomas

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The genes causing familial nonmedullary thyroid carcinoma (FNMTC) identified to date are only involved in a small fraction of the families. Recently, somatic mutations in TERT promoter region and in… Click to show full abstract

The genes causing familial nonmedullary thyroid carcinoma (FNMTC) identified to date are only involved in a small fraction of the families. Recently, somatic mutations in TERT promoter region and in EIF1AX gene were reported in thyroid tumours of undefined familial status. The aim of this study was to investigate the role of TERT and EIF1AX mutations in familial thyroid tumours.

Keywords: mutations familial; tert promoter; nonmedullary thyroid; familial nonmedullary; thyroid

Journal Title: Clinical Endocrinology
Year Published: 2017

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