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An inverse association between serum resistin levels and n‐3 polyunsaturated fatty acids intake was strongest in the SNP‐420 G/G genotype in the Japanese cohort: The Toon Genome Study

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Resistin is secreted by monocytes/macrophages and is associated with insulin resistance, inflammation and cardiovascular diseases. In the Japanese cohort, serum resistin is tightly associated with a single‐nucleotide polymorphism (SNP) at… Click to show full abstract

Resistin is secreted by monocytes/macrophages and is associated with insulin resistance, inflammation and cardiovascular diseases. In the Japanese cohort, serum resistin is tightly associated with a single‐nucleotide polymorphism (SNP) at ‐420 (rs1862513) in the promoter region of the human resistin gene. However, interactions between SNP‐420 and environmental factors remain to be elucidated. The aim of this study was to investigate the association between serum resistin levels and nutrient intake, and the effect of SNP‐420 on this association.

Keywords: resistin; japanese cohort; serum resistin; association serum; snp 420

Journal Title: Clinical Endocrinology
Year Published: 2018

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