Multinodular goitre (MNG) is a common disease, present in 20% of the general population. It is more frequent in females, elderly patients, and low iodine regions. Genetically linked loci for… Click to show full abstract
Multinodular goitre (MNG) is a common disease, present in 20% of the general population. It is more frequent in females, elderly patients, and low iodine regions. Genetically linked loci for familial MNG were found on chromosome 14: MNG1, on chromosome Xp22: MNG2 and on chromosome 3 3q26.1-q26.3: MNG3. DICER1 is the gene identified on chromosome 14 as MNG11 , while MNG2 and MNG3 represent still unknown genes. This article is protected by copyright. All rights reserved.
               
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