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Mifepristone, a glucocorticoid receptor antagonist, can be used to manage hypercortisolism in patients with ectopic adrenocorticotropic hormone syndrome (EAS) when surgical cure is not feasible. Outcomes of EAS patients treated… Click to show full abstract
Mifepristone, a glucocorticoid receptor antagonist, can be used to manage hypercortisolism in patients with ectopic adrenocorticotropic hormone syndrome (EAS) when surgical cure is not feasible. Outcomes of EAS patients treated with mifepristone have been limited to reports of isolated cases. We aimed to determine the efficacy and limitations of mifepristone in the treatment of EAS and to compare outcomes with those of patients who underwent bilateral adrenalectomy.
Keywords:
adrenocorticotropic hormone;
mifepristone treatment;
ectopic adrenocorticotropic;
hormone syndrome
Journal Title: Clinical Endocrinology
Year Published: 2018
Link to full text (if available)
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Journal Title: Clinical Endocrinology
Year Published: 2018
Link to full text (if available)
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recommendations!