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Adipocyte expression of glucose transporter 1 and 4 in PCOS: Relationship to insulin‐mediated and non–insulin‐mediated whole‐body glucose uptake

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Polycystic ovary syndrome (PCOS) is a highly prevalent endocrine‐metabolic disorder associated with insulin resistance (IR). In IR states, non–insulin‐mediated glucose uptake (NIMGU) may increase to compensate for declining insulin‐mediated glucose… Click to show full abstract

Polycystic ovary syndrome (PCOS) is a highly prevalent endocrine‐metabolic disorder associated with insulin resistance (IR). In IR states, non–insulin‐mediated glucose uptake (NIMGU) may increase to compensate for declining insulin‐mediated glucose uptake (IMGU), although this does not appear to be the case in PCOS. The underlying molecular mechanisms for this deficiency remain unclear.

Keywords: insulin; pcos; non insulin; glucose uptake; adipocyte expression; insulin mediated

Journal Title: Clinical Endocrinology
Year Published: 2019

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