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Paediatric and young adult manifestations and outcomes of multiple endocrine neoplasia type 1

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Multiple endocrine neoplasia 1 (MEN 1) is an autosomal dominant disease presenting as hyperplasia and neoplasia of parathyroid, pituitary and enteropancreatic tissues. Over 90% of gene carriers develop phenotypic disease… Click to show full abstract

Multiple endocrine neoplasia 1 (MEN 1) is an autosomal dominant disease presenting as hyperplasia and neoplasia of parathyroid, pituitary and enteropancreatic tissues. Over 90% of gene carriers develop phenotypic disease by age 30 years, potentially with onset of asymptomatic disease during childhood and adolescence.

Keywords: endocrine neoplasia; young adult; paediatric young; multiple endocrine

Journal Title: Clinical Endocrinology
Year Published: 2019

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