LAUSR

OBJECTIVES To evaluate outcome measures, methods of assessment and analysis in clinical studies on fixed single- and multiple- unit implant restorations. METHODS Three independent electronic database searches (MEDLINE, EMBASE, COCHRANE) were done to identify prospective and retrospective clinical studies published from January 2011 up to June 2021 with ≥20 patients and minimum 1 year follow-up period on technical and clinical outcomes of implant-supported single crowns (SCs) and partial fixed dental prostheses (P-FDPs). An entire data extraction was performed to identify primarily the most reported outcome measures and later to define the choice of assessment methods of those outcome measures. The outcomes were analysed descriptively, and the strength of association was evaluated using Pearson Chi-square test (p≤0.05). RESULTS In total 531 studies, 368 on SCs (69.3%), 70 on P-FDPs (13.1%), and 93 on both restoration types (17.5%) were included. 56.3% of all studies did not clearly define a primary outcome. The most frequent primary outcome was marginal bone-level (MBL) (55.2%) followed by implant survival (5.3%), professional esthetic evaluation (3.4%) and technical complications (2.1%). Peri-implant indices were the most reported secondary outcome (55.1%) followed by implant survival (39.9%), MBL (36%) and implant success (26.4%). Prosthetic failure (7 studies - 3.9%) was one of the least reported outcome measures CONCLUSIONS: Outcome measures and their assessment methods exhibited high heterogeneity among studies. Primary outcomes were not often defined clearly, and the most frequently selected primary outcome was marginal bone loss. Prosthetic outcomes, implant survival and patient related outcomes remained infrequently reported.