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Comparing patch test results of methylchloroisothiazolinone/methylisothiazolinone tested with both TRUE Test® and 100 ppm using investigator‐loaded chambers

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Methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI), a widely used preservative/biocide, was included in the European baseline series in 1988 at a concentration of 100 ppm (0.01%) in a ratio of 3:1 (1). Although… Click to show full abstract

Methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI), a widely used preservative/biocide, was included in the European baseline series in 1988 at a concentration of 100 ppm (0.01%) in a ratio of 3:1 (1). Although recently it has been recommended to be tested at 200 ppm (0.02%), many centres still test it at 100 ppm (2). MCI/MI is also included in the TRUE Test®, offering an alternative patch test technique. The objective of the current investigation was to compare the diagnostic performance of MCI/MI 0.01% aq. with MCI/MI in the TRUE Test®.

Keywords: test 100; patch test; true test; test; 100 ppm

Journal Title: Contact Dermatitis
Year Published: 2018

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