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Systemic delayed hypersensitivity reaction to chlorambucil: a case report and literature review

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Conflict of interest: The authors declare no conflict of interests. Chlorambucil is an alkylating agent and a stable derivative of nitrogen mustard. It is primarily used for the treatment of… Click to show full abstract

Conflict of interest: The authors declare no conflict of interests. Chlorambucil is an alkylating agent and a stable derivative of nitrogen mustard. It is primarily used for the treatment of several chronic lymphoproliferative diseases. The drug is generally well tolerated. Significant acute toxicities are dose-related bone marrow depression (leukopenia and thrombocytopenia), gastrointestinal tract symptoms (anorexia, nausea, and vomiting), and neurotoxic manifestations. Cutaneous adverse drug

Keywords: delayed hypersensitivity; systemic delayed; chlorambucil case; reaction chlorambucil; hypersensitivity reaction; case report

Journal Title: Contact Dermatitis
Year Published: 2018

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