Sulfites are widely used as preservatives and antioxidants in food and beverages, but also in cosmetic and pharmaceutical products (1) and medical devices (2). Allergic contact dermatitis caused by sodium… Click to show full abstract
Sulfites are widely used as preservatives and antioxidants in food and beverages, but also in cosmetic and pharmaceutical products (1) and medical devices (2). Allergic contact dermatitis caused by sodium metabisulfite has been increasingly recognized in recent years, and positive patch test reactions seem to be relevant in most patients if carefully investigated (3, 4). Furthermore, systemic allergic reactions to sulfites have also been described following oral and/or parenteral exposure (5–7).
               
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