LAUSR

CASE REPORT An 11-year-old girl with a personal history of asthma and rhinitis presented with persistent recalcitrant hand eczema, affecting predominantly the dorsal aspects of the fingers, despite topical corticosteroids. The child's mother was a nail aesthetician and the patient reported frequent manipulation and “playing” of the child with the mother's professional products, in particular those used for nail aesthetics. Taking this information into account, patch testing was performed with the Portuguese Contact Dermatitis Research Group baseline series, as well as with a few (meth)acrylates apart from 2-HEMA (hydroxyethyl methacrylate) present in the baseline series. Allergens were applied in IQ-ultra chambers (Chemotechnique Diagnostics, Vellinge Sweden) on the back for 48 hours and readings were performed on day (D) 3 and D7, according to ESCD guidelines. Strong (++) reactions to 2-HEMA, hydroxypropyl methacrylate (HPMA), hydroxyethyl acrylate (HEA), ethyleneglycol dimethacrylate (EGDMA), and urethane dimethacrylate (UDMA) were observed (Figure 1A,B). Weak positive (+) reactions to methylisothiazolinone and methyldibromo glutaronitrile were also present. Hand eczema resolved after avoidance of the above-mentioned products, thus confirming the diagnosis of hand eczema due to nail (meth)acrylate allergy in this child. The mother was informed about other possible sources of exposure that may affect future