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Experience of the implementation and outcomes of universal testing for Lynch syndrome in the United Kingdom

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Colorectal cancer (CRC) is diagnosed in approximately 45 000 people annually in the UK, and it is estimated that Lynch syndrome (LS) accounts for 3.1% of these cases. In February… Click to show full abstract

Colorectal cancer (CRC) is diagnosed in approximately 45 000 people annually in the UK, and it is estimated that Lynch syndrome (LS) accounts for 3.1% of these cases. In February 2017, National Institute for Health and Care Excellence (NICE guideline DG27 recommended universal testing of new cases of CRC for mismatch repair (MMR) status. The aim of this study was to implement universal testing for LS in CRC patients in a secondary care setting.

Keywords: universal testing; outcomes universal; implementation outcomes; testing lynch; lynch syndrome; experience implementation

Journal Title: Colorectal Disease
Year Published: 2019

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