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Patient‐ and physician‐reported radiation‐induced toxicity of short‐course radiotherapy with a prolonged interval to surgery for rectal cancer

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A prolonged interval (>4 weeks) between short‐course radiotherapy (25 Gy in five fractions) (SCRT‐delay) and total mesorectal excision for rectal cancer has been associated with a decreased postoperative complication rate and offers… Click to show full abstract

A prolonged interval (>4 weeks) between short‐course radiotherapy (25 Gy in five fractions) (SCRT‐delay) and total mesorectal excision for rectal cancer has been associated with a decreased postoperative complication rate and offers the possibility of organ preservation in the case of a complete tumour response. This prospective cohort study systematically evaluated patient‐reported bowel dysfunction and physician‐reported radiation‐induced toxicity for 8 weeks following SCRT‐delay.

Keywords: physician reported; prolonged interval; short course; course radiotherapy; reported radiation; rectal cancer

Journal Title: Colorectal Disease
Year Published: 2022

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