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Simultaneous integrated boost intensity‐modulated radiation therapy targeting clinically involved extramesorectal lymph nodes in locally advanced rectal cancer: A retrospective study

Consensus is lacking regarding the management of extramesorectal lymph nodes (EMLN) in rectal cancer. Using simultaneous integrated boost intensity‐modulated radiation therapy (SIB‐IMRT), we targeted involved EMLN and reserved lateral pelvic… Click to show full abstract

Consensus is lacking regarding the management of extramesorectal lymph nodes (EMLN) in rectal cancer. Using simultaneous integrated boost intensity‐modulated radiation therapy (SIB‐IMRT), we targeted involved EMLN and reserved lateral pelvic lymph nodal dissection (LPLND) for nonresponders. The primary aim of this work was to determine the proportion of patients who avoided LPLND and to establish the pathological EMLN positivity rate.

Keywords: extramesorectal lymph; lymph; simultaneous integrated; lymph nodes; rectal cancer; integrated boost

Journal Title: Colorectal Disease
Year Published: 2025

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